Searchable abstracts of presentations at key conferences in endocrinology

Endocrine Abstracts

Published by BioScientifica

Page 2 of about 42 results

ea0056p673 | Nuclear receptors and Signal transduction | ECE2018

Vitamin D abolishes the dexamethasone-induced apoptosis in acute myeloid leukemia cells via regulation of Notch signaling

Karapanagioti Angeliki G , Nasiri-Ansari Narjes , Angelousi Anna , Kalotychou Vasiliki , Papavasilliou Athanasios G , Kassi Eva

Introduction: Glucocorticoids are used for treatment of various hematological malignancies such as Acute Myeloid Leukemia (AML). Glucocorticoids are known to induce apoptosis by regulating the expression of key anti- or pro-apoptotic genes. Vitamin D induces apoptosis and cell cycle arrest in various types of cancer cells. Despite recent advances in treatment of AML, the poor response rate to therapy remains a big challenge.Therefore, discovering new factors that can affect th...
0 shares

ea0073oc14.4 | Oral Communications 14: Across Endocrinology | ECE2021

Evaluation of the hypothalamic-pituitary-adrenal axis suppression in kidney transplant recipients and its association with metabolic parameters

Angelousi Anna , Tsiakas Stathis , Xagas Efstathios , Athanasouli Fani , Marinaki Smaragdi , Boletis Ioannis

IntroductionCorticosteroids are included in the maintenance immunosuppressive regimen in most kidney transplant recipients. Studies evaluating the effect of chronic low-dose glucocorticoid treatment on the hypothalamic-pituitary-adrenal (HPA) axis and the metabolic profile of these patients are limited.AimThe objective of the study was to evaluate the metabolic effects and the alterations of HPA axis regulati...
0 shares

ea0073aep49 | Adrenal and Cardiovascular Endocrinology | ECE2021

Hair cortisol levels in patients with adrenal incidentalomas compared to healthy controls

Athanasouli Fani , Mytareli Chrysoula , Andreadaki Evangelia , Petychaki Foteini , Savelli Akrivi , Asonitis Nikos , Anna Angelousi

BackgroundAdrenal incidentalomas (AI) are present in 3–10% of the general population. Up to 20% of them may have autonomous cortisol secretion (ACS). However, subclinical hypercortisolism isn’t clearly defined. The 1mg dexamethasone suppression test (ODST) is the most widely accepted for the screening of these patients. Recent data suggest that hair cortisol should be considered as a routine test for the screening of Cushing syndrome.<p cla...
0 shares

ea0099rc11.7 | Rapid Communications 11: Adrenal and Cardiovascular Endocrinology | Part II | ECE2024

An artificial intelligence-based decision support system for classifying patients with adrenal tumors

Binas Dimitrios , Economopoulos Theodore , Betsi Grigoria , Xekouki Paraskevi , Angelousi Anna , Matsopoulos George

Background: Adrenal Incidentaloma’s (AI) incidence has been increased 10-fold in the past two decades and more specifically, up to 7% in the general population and up to 9% in elderly patients. Determining whether an adrenal mass is malignant or hormonally active is of great clinical and socioeconomical importance, in order to select the best medical approach and follow up. Artificial Intelligence techniques could provide useful clinical tools for predicting the nature of...
0 shares

ea0090ep173 | Calcium and Bone | ECE2023

The effect of Immune Checkpoint Inhibitors (ICIs) in Bone Metabolism: A case series analysis

Siampanopoulou Vasiliki , Angelousi Anna , Karampela Athina , Papalexis Petros , Lafioniatis Alexandros , Mytareli Chrysoula , Ziogas Dimitrios , Gogas Helen , Kassi Evanthia

Background: Immune checkpoint inhibitors (ICIs) constitutes a novel treatment for patients with melanoma. Endocrine-related adverse effects are now a distinctive clinical entity of ICIs, with hypophysitis and thyroiditis being the most common. Recent consensus doesn’t suggest routinely screening of bone mass indexes in patients on ICIs since data in the literature are scarce.Methods: Data regarding bone disease were retrospectively analysed in 118 p...
1 shares

ea0049gp236 | Thyroid Cancer &amp; Thyroid Case Reports | ECE2017

A rare case of medullary thyroid cancer, mesothelioma and meningioma, due to APC and RASAL1 mutations

Lyssikatos Charalampos , Quezado Martha M , Faucz Fabio R , Angelousi Anna , Nasiri-Ansari Narjes , Stratakis Constantine A , Kassi Eva

Introduction: Patients with “mixed” phenotypes are common among patients with multiple endocrine and non-endocrine neoplasias. Their diagnoses do not fit a given pattern making ge netic counseling difficult and testing impossible to guide. Most of these patients end up getting genome-wide studies for the identification of any predisposing genetic defect. We present a rare case of a 57 year old female who presented clinically with medullary thyroid cancer (MTC), mesot...
0 shares

ea0059p134 | Neuroendocrinology and pituitary | SFEBES2018

Prolactin as a surrogate marker of prolactinoma diagnosis in PCOS

Dimitriadis Georgios K , Kyritsi Eleni Magdalini , Angelousi Anna , Mehta Hiten , Shad Amjad , Mytilinaiou Maria , Kaltsas Gregory , Randeva Harpal S

Background: To identify a serum prolactin (PRL) cut-off value indicative of a PRL-producing adenoma in women with polycystic ovarian syndrome (PCOS) and hyperprolactinaemia and characterize such patients. Materials and methods: In the present retrospective case–control study, the medical records of 528 PCOS women were reviewed. Pituitary magnetic resonance imaging (MRI) was performed in PCOS patients with PRL levels ≥94.0 ng/ml and/or symptoms suspicious of a pituit...
0 shares

ea0056gp33 | Adrenal cortex | ECE2018

Alterations in Clock genes expression in human benign adrenal tumors

Angelousi Anna , Nasiri-Ansari Narjes , Karapanagioti Angeliki , Aggeli Chrysanthi , Zografos Georgios , Chrousos Georgios , Kaltsas Gregory , Kassi Eva

Introduction: Alteration in the expression of clock-related genes has been observed in various diseases. Adrenal sensitivity to adrenocorticotropic hormone (ACTH) apart from the hypothalamo-pituitary-adrenal axis is also regulated by the intrinsic adrenal clock. A link between clock genes and glucocorticoid adrenal production has been suggested by in vitro and animal studies. In the present study we investigated clock genes expression in human benign tumors of the adr...
0 shares

ea0099ep258 | Adrenal and Cardiovascular Endocrinology | ECE2024

Psychometric parameters and quality of life in patients with adrenal tumours

Charikleia Tasouli Elisavet , Mytareli Chrysoula , Andreadaki Evangelia , Thanasoula Foteini , Siampanopoulou Vasiliki , Karabela Athina , Papalexis Petros , Lafioniatis Alexandros , Angelousi Anna

Introduction: Neuropsychiatric disorders are common and well-studied in patients with overt hypercortisolism. However, data regarding patients with adrenal incidentalomas (AIs) are limited. The aim of our study is to assess the psychometric and quality of life status in individuals with benign adrenal tumours.Methods: Eighty-two patients diagnosed with AIs, encompassing 53 females and 29 males, with a total mean age of 64 years and 52controls (without AI...
0 shares

ea0099ep255 | Calcium and Bone | ECE2024

An interesting case of co-existence of autosomal dominant hypocalcemia 1 with chronic myelogenous leukemia

Eleni Chondrogianni Maria , Kyrou Ioannis , Papadopoulou Anna , Kaperda Aikaterini , Diamantopoulos Panagiotis , Angelousi Anna , Randeva Harpal , Kassi Eva

Introduction: Autosomal dominant hypocalcemia (ADH) type 1 is a rare form of hypoparathyroidism, caused by heterozygous, inherited or de novo, activating mutations in the CASR. CASR is also expressed in the kidney and activating mutations lead to decreased calcium renal absorption. Activating mutations in the CasR, inhibits salt transport, leading to Bartteŕs syndrome (BS) type V which can co-exist with ADH1. Chronic myeloid leukemia (Cml) is characterized by the...
0 shares

Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 | Privacy policy | Cookie settings

BiosciAbstracts

Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.

Find out more